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Copper peptide Clinical data Human data available

Peptide database · P-004

GHK-Cu

Copper tripeptide-1; Gly-His-Lys-Cu

GHK-Cu is an endogenous copper–tripeptide complex studied particularly in skin-matrix, wound-repair and cell-culture models.

01

Molecular profile

Molecular profile

Molecule class
Copper peptide
Origin
Endogenous complex
Primary target system
Kupfertransport, Matrixremodelling und Genexpressionsnetzwerke
Development stage
Authorised active substance
Structure note

Kupfer(II)-Komplex des Tripeptids Gly-His-Lys.

02

Mechanism and signalling

Mechanism and signalling

GHK binds copper ions with high affinity. Research examines metal homeostasis, collagen and glycosaminoglycan metabolism, and redox-sensitive pathways.

03

Scientific classification

Scientific classification

This profile maps GHK-Cu to the research areas regeneration, dermatology. Molecule class, evidence level, development stage and regulatory status are separated so that preclinical findings are not confused with authorised uses.

Tissue and regeneration research

Peptides studied in models of cell migration, matrix organisation, wound healing and tissue repair.

Dermatology and melanocortin research

Skin matrix, pigmentation biology, copper peptides and melanocortin signalling.

04

Evidence base

Clinical data

PreclinicalEarly human dataClinical dataPhase IIPhase IIIApproval and post-marketing data

Preclinical and smaller human studies exist, especially in cosmetic dermatology. Results cannot be transferred directly to injectable or systemic use.

05

Regulatory status

Status varies by region

Status varies by region

Regulatory status differs by country, product form and intended use. Authorisation in one jurisdiction does not transfer to Germany or the EU.

06

Safety and use notice

No dosing or administration recommendation

The available evidence does not establish safe self-directed use. This profile intentionally provides no dosing, sourcing or administration guidance.

07

Sources and registries

Sources and registries