Molecular profile
Molecular profile
- Molecule class
- Conopeptide
- Origin
- Synthetic analogue
- Primary target system
- N-Typ spannungsabhängige Calciumkanäle (CaV2.2)
- Development stage
- Authorised active substance
Synthetisches Analogon des ω-Conotoxins MVIIA mit drei Disulfidbrücken.
Mechanism and signalling
Mechanism and signalling
It blocks presynaptic N-type calcium channels and thereby reduces release of nociceptive neurotransmitters in the spinal cord.
Scientific classification
Scientific classification
This profile maps Ziconotid to the research areas neuro. Molecule class, evidence level, development stage and regulatory status are separated so that preclinical findings are not confused with authorised uses.
Neuropeptides and analogues in models of neuronal signalling, stress and pain.
Evidence base
Approval and post-marketing data
Approval and clinical experience relate to a tightly controlled specialist procedure. This profile provides no administration details.
Regulatory status
Authorised in the EU/multiple markets
The active substance is used in authorised medicines in multiple jurisdictions. Authorisations apply only to defined products, indications, quality standards and conditions of use.
Safety and use notice
No dosing or administration recommendation
The available evidence does not establish safe self-directed use. This profile intentionally provides no dosing, sourcing or administration guidance.
Sources and registries