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Mitochondrial peptide Preclinical No robust human data

Peptide database · P-026

Humanin

HN; mitochondrial-derived peptide

Humanin is a mitochondrial-derived peptide studied in models of cellular stress, neuroprotection, metabolism and ageing biology.

01

Molecular profile

Molecular profile

Molecule class
Mitochondrial peptide
Origin
Endogenous
Primary target system
Zellstress-, Apoptose- und Rezeptorkomplex-Signalwege
Development stage
Preclinical development
Structure note

Mitochondrial abgeleitetes Peptid; verschiedene Isoformen und Analoga werden untersucht.

02

Mechanism and signalling

Mechanism and signalling

Reported mechanisms include interactions with pro-apoptotic proteins and membrane receptor complexes. Analogues can have substantially different properties.

03

Scientific classification

Scientific classification

This profile maps Humanin to the research areas mitochondrial, neuro. Molecule class, evidence level, development stage and regulatory status are separated so that preclinical findings are not confused with authorised uses.

Mitochondria and longevity research

Mitochondrial peptides, cellular stress, bioenergetics and age-associated pathways.

Neuroactive research

Neuropeptides and analogues in models of neuronal signalling, stress and pain.

04

Evidence base

Preclinical

PreclinicalEarly human dataClinical dataPhase IIPhase IIIApproval and post-marketing data

Research is dominated by cell and animal models. Clinical validation, standardised biomarkers and robust safety data are lacking.

05

Regulatory status

Not generally authorised

Not generally authorised

This research substance has no general medicinal authorisation in Germany or the EU. Labels such as “research peptide” do not replace regulatory approval.

06

Safety and use notice

No dosing or administration recommendation

The available evidence does not establish safe self-directed use. This profile intentionally provides no dosing, sourcing or administration guidance.

07

Sources and registries

Sources and registries