Molecular profile
Molecular profile
- Molecule class
- Mitochondrial peptide
- Origin
- Endogenous
- Primary target system
- AMPK-assoziierte Stress- und Stoffwechselantworten
- Development stage
- Preclinical development
Mitochondrial kodiertes Peptid aus dem 12S-rRNA-Locus.
Mechanism and signalling
Mechanism and signalling
Experimental models describe AMPK-related stress responses, metabolite signalling and possible translocation to the nucleus.
Scientific classification
Scientific classification
This profile maps MOTS-c to the research areas mitochondrial, metabolism. Molecule class, evidence level, development stage and regulatory status are separated so that preclinical findings are not confused with authorised uses.
Mitochondrial peptides, cellular stress, bioenergetics and age-associated pathways.
Pathways related to glucose homeostasis, appetite, energy expenditure and body composition.
Evidence base
Preclinical
Evidence is predominantly preclinical. The FDA reports that it has not identified adequate human-exposure data for related compounded products.
Regulatory status
Not generally authorised
This research substance has no general medicinal authorisation in Germany or the EU. Labels such as “research peptide” do not replace regulatory approval.
Safety and use notice
No dosing or administration recommendation
The available evidence does not establish safe self-directed use. This profile intentionally provides no dosing, sourcing or administration guidance.
Sources and registries