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Endogenous peptide Clinical data Human data available

Peptide database · P-017

Kisspeptin-10

Metastin(45-54); KP-10

Kisspeptin-10 is an active KISS1-derived fragment and a key research modulator of the hypothalamic reproductive axis.

01

Molecular profile

Molecular profile

Molecule class
Endogenous peptide
Origin
Endogenous fragment
Primary target system
KISS1R/GPR54 und GnRH-Achse
Development stage
Clinical development
Structure note

Aktives C-terminales Fragment von Kisspeptin.

02

Mechanism and signalling

Mechanism and signalling

KISS1R activation stimulates GnRH neurons and influences downstream LH and FSH signalling.

03

Scientific classification

Scientific classification

This profile maps Kisspeptin-10 to the research areas reproductive, endocrine. Molecule class, evidence level, development stage and regulatory status are separated so that preclinical findings are not confused with authorised uses.

Reproductive and social neuroendocrinology

Peptide signals related to reproductive axes, social behaviour and sexual function.

Endocrine signalling

Peptide hormones and analogues related to hypothalamic, pituitary and peripheral endocrine systems.

04

Evidence base

Clinical data

PreclinicalEarly human dataClinical dataPhase IIPhase IIIApproval and post-marketing data

Controlled human studies investigate reproductive and diagnostic questions. Use remains research- or trial-specific.

05

Regulatory status

Investigational substance

Investigational substance

The substance remains in clinical development and is not authorised as a generally available medicine. Trial status and regulatory assessment may change.

06

Safety and use notice

No dosing or administration recommendation

The available evidence does not establish safe self-directed use. This profile intentionally provides no dosing, sourcing or administration guidance.

07

Sources and registries

Sources and registries