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Cyclic peptide Early human data Human data available

Peptide database · P-021

Melanotan II

MT-II; melanotan 2

Melanotan II is an unapproved cyclic alpha-MSH analogue that activates multiple melanocortin receptors.

01

Molecular profile

Molecular profile

Molecule class
Cyclic peptide
Origin
Synthetic analogue
Primary target system
MC1R, MC3R, MC4R und weitere Melanocortinrezeptoren
Development stage
Clinical development
Structure note

Zyklisches alpha-MSH-Analogon mit nichtselektiver Melanocortinrezeptor-Aktivität.

02

Mechanism and signalling

Mechanism and signalling

Non-selective receptor activation can affect pigmentation, appetite, cardiovascular and sexual-function signals simultaneously.

03

Scientific classification

Scientific classification

This profile maps Melanotan II to the research areas dermatology, reproductive. Molecule class, evidence level, development stage and regulatory status are separated so that preclinical findings are not confused with authorised uses.

Dermatology and melanocortin research

Skin matrix, pigmentation biology, copper peptides and melanocortin signalling.

Reproductive and social neuroendocrinology

Peptide signals related to reproductive axes, social behaviour and sexual function.

04

Evidence base

Early human data

PreclinicalEarly human dataClinical dataPhase IIPhase IIIApproval and post-marketing data

Early human studies coexist with uncontrolled use and case reports. Verified medicinal quality and general approval are absent.

05

Regulatory status

Not generally authorised

Not generally authorised

This research substance has no general medicinal authorisation in Germany or the EU. Labels such as “research peptide” do not replace regulatory approval.

06

Safety and use notice

No dosing or administration recommendation

The available evidence does not establish safe self-directed use. This profile intentionally provides no dosing, sourcing or administration guidance.

07

Sources and registries

Sources and registries