Molecular profile
Molecular profile
- Molecule class
- Antimicrobial peptide
- Origin
- Endogenous
- Primary target system
- Membraninteraktion, angeborene Immunität und Immunmodulation
- Development stage
- Clinical development
Kationisches amphipathisches Peptid aus dem humanen Cathelicidin-Vorläufer.
Mechanism and signalling
Mechanism and signalling
The cationic peptide can disrupt microbial membranes and also interacts with host-cell receptors, nucleic acids and inflammatory networks.
Scientific classification
Scientific classification
This profile maps LL-37 to the research areas immune, dermatology. Molecule class, evidence level, development stage and regulatory status are separated so that preclinical findings are not confused with authorised uses.
Innate immunity, epithelial barriers and antimicrobial peptide functions.
Skin matrix, pigmentation biology, copper peptides and melanocortin signalling.
Evidence base
Early human data
Biological effects are highly context-dependent: concentration, ionic environment and tissue can favour protective or pro-inflammatory responses. Clinical development remains indication-specific.
Regulatory status
Not generally authorised
This research substance has no general medicinal authorisation in Germany or the EU. Labels such as “research peptide” do not replace regulatory approval.
Safety and use notice
No dosing or administration recommendation
The available evidence does not establish safe self-directed use. This profile intentionally provides no dosing, sourcing or administration guidance.
Sources and registries