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Peptide analogue Approval and post-marketing data Human data available

Peptide database · P-008

Semaglutide

Semaglutide; GLP-1 receptor agonist

Semaglutide is a modified GLP-1 analogue used in authorised medicines for defined metabolic indications.

01

Molecular profile

Molecular profile

Molecule class
Peptide analogue
Origin
Synthetic analogue
Primary target system
GLP-1-Rezeptor
Development stage
Authorised active substance
Structure note

Langwirksames, acyliertes GLP-1-Analogon.

02

Mechanism and signalling

Mechanism and signalling

As a GLP-1 receptor agonist it affects glucose-dependent insulin secretion, glucagon release, gastric emptying and central satiety signalling.

03

Scientific classification

Scientific classification

This profile maps Semaglutid to the research areas metabolism, endocrine. Molecule class, evidence level, development stage and regulatory status are separated so that preclinical findings are not confused with authorised uses.

Metabolism and energy regulation

Pathways related to glucose homeostasis, appetite, energy expenditure and body composition.

Endocrine signalling

Peptide hormones and analogues related to hypothalamic, pituitary and peripheral endocrine systems.

04

Evidence base

Approval and post-marketing data

PreclinicalEarly human dataClinical dataPhase IIPhase IIIApproval and post-marketing data

Clinical evidence includes large randomised programmes and post-marketing data. Assessment and safety must remain product- and indication-specific.

05

Regulatory status

Authorised in the EU/multiple markets

Authorised in the EU/multiple markets

The active substance is used in authorised medicines in multiple jurisdictions. Authorisations apply only to defined products, indications, quality standards and conditions of use.

06

Safety and use notice

No dosing or administration recommendation

The available evidence does not establish safe self-directed use. This profile intentionally provides no dosing, sourcing or administration guidance.

07

Sources and registries

Sources and registries