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Peptide analogue Approval and post-marketing data Human data available

Peptide database · P-009

Tirzepatide

Tirzepatide; dual GIP/GLP-1 receptor agonist

Tirzepatide is a long-acting peptide analogue with dual GIP and GLP-1 receptor activity used in authorised medicines.

01

Molecular profile

Molecular profile

Molecule class
Peptide analogue
Origin
Synthetic analogue
Primary target system
GIP- und GLP-1-Rezeptoren
Development stage
Authorised active substance
Structure note

Langwirksames, acyliertes duales GIP/GLP-1-Rezeptoragonisten-Peptid.

02

Mechanism and signalling

Mechanism and signalling

Combined incretin-receptor activation affects glucose-dependent endocrine signals, food intake and metabolic regulation.

03

Scientific classification

Scientific classification

This profile maps Tirzepatid to the research areas metabolism, endocrine. Molecule class, evidence level, development stage and regulatory status are separated so that preclinical findings are not confused with authorised uses.

Metabolism and energy regulation

Pathways related to glucose homeostasis, appetite, energy expenditure and body composition.

Endocrine signalling

Peptide hormones and analogues related to hypothalamic, pituitary and peripheral endocrine systems.

04

Evidence base

Approval and post-marketing data

PreclinicalEarly human dataClinical dataPhase IIPhase IIIApproval and post-marketing data

Large phase III programmes and regulatory assessments are available. Conclusions apply only to authorised products and the populations studied.

05

Regulatory status

Authorised in the EU/multiple markets

Authorised in the EU/multiple markets

The active substance is used in authorised medicines in multiple jurisdictions. Authorisations apply only to defined products, indications, quality standards and conditions of use.

06

Safety and use notice

No dosing or administration recommendation

The available evidence does not establish safe self-directed use. This profile intentionally provides no dosing, sourcing or administration guidance.

07

Sources and registries

Sources and registries